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+ servings
close up of pizza being baked in a casserole dish
4.5 from 11 votes
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Yield: 4 -6 servings

Pizza Casserole

This Pizza Casserole is so quick and easy! Plus, you only need four simple ingredients - sauce, cheese, refrigerated biscuits, and pepperoni.
Prep Time10 minutes
Cook Time40 minutes
Total Time50 minutes

Ingredients

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Instructions 

  • 1. Preheat the oven to 350°F. Prepare a 9x13 baking pan with cooking spray, set aside.
  • 2. Cut the biscuits into quarters and layer them in the bottom of the prepared dish. Pour the pizza sauce over the biscuits, making sure to get sauce in all of the nooks and crannies.
  • 3. Sprinkle a little bit of the cheese, add some pepperoni, and then add another layer of cheese and pepperoni. We get more pepperoni in this way without just covering the top in a solid layer of pepperoni.
  • 4. Top with foil and bake for 20 minutes, then remove the foil and bake for an additional 20 to 25 minutes, or until cheese is melted and just starting to brown.
  • 5. Let rest for 5 minutes for casserole to set up, then serve!

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Nutrition

Serving: 1, Calories: 600kcal, Carbohydrates: 20g, Protein: 35g, Fat: 42g, Saturated Fat: 20g, Polyunsaturated Fat: 18g, Trans Fat: 1g, Cholesterol: 109mg, Sodium: 1616mg, Fiber: 1g, Sugar: 5g